A Modified Synthesis of (+-)-2-2'-Spirobi[indan]-1,1'-dione.
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چکیده
منابع مشابه
Synthesis and Evaluation of Anti-acetylcholinesterase Activity of 2-(2-(4-(2-Oxo-2-phenylethyl)piperazin-1-yl) ethyl)Isoindoline-1,3-dione Derivatives with Potential Anti-Alzheimer Effects
Objective(s): Alzheimer's disease (AD) is a neurodegenerative disorder in elderly patients. Decrease in cholinergic neurotransmission is the main known cause in the pathophysiology of the disease. Improvement and potentiation of the cholinergic system could be beneficial for treatment of the AD. Acetylcholinesterase inhibitors such as donepezil can enhance the duration of action of a...
متن کاملSynthesis and Biological Evaluation of 4-hydroxychromenyl arylmethyl-6-hydroxy pyrimidine-2, 4-dione Derivatives
Background: An efficient, promoted tri-component catalytic reaction between barbituric acid (or N,N-dimethyl barbituric acid), 4-hydroxy coumarin, and a wide range of aryl aldehydes using zinc oxide nanowires (ZnO NWs) to obtain some new 4-hydroxychromenylarylmethyl-6-hydroxypyrimidine-2,4-diones is described. Method: The reactants were successfully condensed ...
متن کاملsynthesis and evaluation of anti-acetylcholinesterase activity of 2-(2-(4-(2-oxo-2-phenylethyl)piperazin-1-yl) ethyl)isoindoline-1,3-dione derivatives with potential anti-alzheimer effects
objective(s): alzheimer's disease (ad) is a neurodegenerative disorder in elderly patients. decrease in cholinergic neurotransmission is the main known cause in the pathophysiology of the disease. improvement and potentiation of the cholinergic system could be beneficial for treatment of the ad. acetylcholinesterase inhibitors such as donepezil can enhance the duration of action of acetylc...
متن کامل2-Methoxynaphthalene-1,4-dione
The title compound, C(11)H(8)O(3), was isolated from Impatiens balsamina plants (balsam, LIB) grown in our laboratory. The two six-membered rings of the naphthalene-1,4-dione unit are coplanar [maximum deviation = 0.009 (1) Å]. The O and C atoms of the meth-oxy substituent also lie close to the naphthalene plane, with deviations of 0.0090 (2) and 0.047 (2) Å, respectively.
متن کامل2-(2-Bromoethyl)isoindoline-1,3-dione
The asymmetric unit of the title compound, C(10)H(8)BrNO(2), contains three crystallographically independent mol-ecules. Two of the N-C-C-Br side chains adopt anti conformations [torsion angles = -179.8 (5) and -179.4 (4)°] and the other is gauche [-66.5 (6)°]. The crystal structure features short Br⋯O [3.162 (5) Å] contacts, C-H⋯O hydrogen bonds and numerous π-π stacking inter-actions [centroi...
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ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1972
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.26-0850